Sensitivity and specificity of anti-Jo-1 antibodies in autoimmune diseases with myositis
نویسندگان
چکیده
منابع مشابه
Anti Jo-1 myositis. 'Mechanic's hands' and interstitial lung disease.
We report three patients who presented with painful weak muscles, a violaccous rash on the extensor aspect of their hands, elevated muscle enzymes, electromyographic and muscle biopsy findings typical ofpolymyositis. All three patients had anti JoI autoantibodies, 'mechanic's hands' and evidence of interstitial lung disease on CT scan. An incomplete response to corticosteroids was observed in a...
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متن کاملExpression of BAFF receptors in muscle tissue of myositis patients with anti-Jo-1 or anti-Ro52/anti-Ro60 autoantibodies
INTRODUCTION Anti-Jo-1 and anti-Ro52 autoantibodies are common in patients with myositis, but the mechanisms behind their production are not known. Survival of autoantibody-producing cells is dependent on B-cell-activating factor of the tumour necrosis factor family (BAFF). BAFF levels are elevated in serum of anti-Jo-1-positive myositis patients and are influenced by type-I interferon (IFN). I...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1996
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780390218